LPDG

-- The London Proteomics Discussion Group --
Proteomics seminar series for the South East

7th August 2020
Proteomics seminar series for the South East
Discussion
Networking
Methods Challenge
---Registration is free---

About the LPDG

We are a free, local proteomics seminar series in the South East,
with a focus towards networking, discussion and supporting early career researchers.

The LPDG...

was founded to bring together the large community of proteomics scientists all working in and around London. We aim to provide a space for discussion, with a focus on methods and early career researchers (two fundamental building blocks of good research!), on all topics related to proteomics. The meetings comprise of research talks framed by a proteomics methods challenge, lunch, refreshments and pizza - they are free to attend thanks to sponsorship.


Meeting Dates:

Next Meeting

Sponsors

These seminars would not be possible without our amazing sponsors.
If you are interested in sponsoring an LPDG seminar,
please get in touch at sponsor@londonproteomics.co.uk

Webinar Programme


Proteomics: Beyond the Horizon

for 7th August 2020 14:00 BST
Last updated 24th July 2020

Prof Claire Eyers

The Expanding Landscape of Human Protein Phosphorylation

Abstract to follow shortly.

Dr Ben Neely

Exploring the Protein Landscape in Non-model Systems: Insights into Potential Host-virus Interactions and Disease Resistance

The current SARS-CoV-2 pandemic has highlighted the scientific community’s ability to prioritize existing relevant research and accelerate new research. Proteomics is playing a pivotal role in these advancements including mass spectrometry-based virus detection, diagnostic and prognostic biomarkers of COVID-19 severity and identifying new disease treatment targets. Given that the majority of the current research is focused on human-virus interactions, it is important to also note that betacoronaviruses and other viruses also interact with countless other mammals with which we have varying degrees of biochemical similarity. Therefore studying these other systems may provide insight into infection and virulence. Using a recent data-independent acquisition-based shotgun proteomic analysis of vampire bat (Desmodus rotundus) serum, we demonstrate the possible benefits and insight to applying the same technical tools used in SARS-CoV-2 research to a non-human system. Moreover, these types of studies in non-model systems can improve our understanding of longevity, ischemia/reperfusion injury resistance and cancer. It seems now more than ever that proteomics can and should expand into non-model systems, not only with regards to SARS-CoV-2 but also to help advance biomedical discovery.

Event Speakers

Would you like to present at an LPDG meeting? Email: speaker@londonproteomics.co.uk
Research presentations from:

Prof Claire Eyers
Prof Claire Eyers
Prof Claire Eyers University of Liverpool

Claire E Eyers is Professor of Biological Mass Spectrometry in the Institute of Systems, Molecular & Integrative Biology at the University of Liverpool, Director of the Centre for Proteome Research, and Deputy APVC for the Faculty of Health and Life Sciences. Her research is to understand the relevance of PTMs and their roles in regulating cellular signalling in health and disease. She has expertise in the development of MS-based methods, using separation technologies including ion mobility, for the investigation of proteins, the effects of PTMs and ligand binding.

Dr Ben Neely
Dr Ben Neely
Dr Ben Neely National Institute of Standards and Technology
South Carolina, USA

Dr Neely is a research chemist with NIST. His diverse background includes microbiology, wildlife disease, cancer biology, biomarker discovery and validation (peptide, protein and glycan) and bioinformatics. Currently he is focused on large-scale generation of standardized proteomic data (including data-independent acquisition) across non-model mammalian species.

Prof Kathryn Lilley
Prof Kathryn Lilley
Prof Kathryn Lilley Guest Chair
Jeffrey Cheah Biomedical Centre,
University of Cambridge

Kathryn Lilley is a Professor in the Department of Biochemistry and a member of the Milner Therapeutics Institute. She is also Director of the Cambridge Centre for Proteomics, and a Director of Studies at Jesus College. The Lilley Group focuses on the development and application of technologies to measurement the dynamic proteome in space and time in cells in a high-throughput manner. More specifically, we are interested in looking at the changes in abundance, location, interacting partners, PTM status and structure of proteins during dynamic cellular processes such as differentiation.

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FAQ

Here is a list of answers to frequently asked questions for speakers, delegates and sponsors

If you still have unanswered questions after reading this page, wish to present a talk, suggest a venue or sponsor a meeting, please contact us.

Organising Committee

The organising committee is made up of early and "not-so-early" career scientists
from academia and industry.
If you are interested in joining the committee, please get in touch.

Dr Harvey Johnston
Dr Harvey Johnston Chairperson, Founder

After my PhD in blood plasma cancer proteomics I moved to the Cancer Proteomics Group at UCL. I founded the LPDG as a focus group for the SE. I am currently at the Babraham Institute investigating protein degradation pathways using proteomics.

Dr Harry Whitwell
Dr Harry Whitwell Communications Officer

I am a post doc at ICL, developing mass spectrometry and data analysis methodology for the study of protein PTMs, in particular methylation. My research is multidisciplinary, using chemistry, bioinformatics and biology. For more info, click here.

Dr Lukas Krasny
Dr Lukas Krasny Secretary

I am a post-doc at the ICR in Paul Huang’s group. My research interest is in extracellular matrix remodelling during cancer progression. From an analytical point of view, I am interested in protein quantification by DIA mass spectrometry.

Dr Roberto Buccafusca
Dr Roberto Buccafusca Treasurer

I manage an MS lab at QMUL. I graduated from Drexel University (USA) in Biomedical Science, completing my PhD work at Harvard University. After a long stint in the private sector, I re-joined academia here in the UK researching lipidomics and proteomics.

Danai Kati
Danai Kati
Danai Kati Committee Member

Danai studied biology and biomedical sciences in Greece. She has worked in numerous labs in England, Singapore, the Netherlands and Greece. Now she is focusing on her PhD at UCL in Primary Biliary Cholangitis analyzing human samples using Mass spectrometry.

Suniya Khatun
Suniya Khatun Committee member

I am a PhD student at UCL on the CellX project in the Thalassinos Lab studying competition in cellular populations using mass spectrometry-based proteomics.

Dr Daniel Conole
Dr Daniel Conole Committee member

Daniel is a post-doc in the lab of Prof. Ed Tate at Imperial College London. His research interests lie in the use of chemical proteomics for better understanding of drug targets, protein function, and post-translational modification dynamics.

Tom Ruane
Tom Ruane Committee member

Tom works for SCIEX in the London region helping customers with MS and 'OMICS applications. He gained an interest in MS from working with Prof Roy Goodacre, Manchester Institute of Biotech. applying -omics and chemometric approaches for rapid food authenticity determination.

Emily Vitterso
Emily Vitterso Committee member

I am a PhD student in the Institute for Women's Health, UCL in the lab of Dr John Timms working on cancer proteomics.

Joanna Kirkpatrick
Dr Joanna Kirkpatrick
Dr Joanna Kirkpatrick Committee member

Joanna Kirkpatrick
Crick Insitute

London and the South East
United Kindgom

Please email with any questions.
Particularly welcome are venue suggestions,
speaker suggestions or if you are thinking of sponsoring a meeting.

This seminar series is run by volunteers from academia and industry. We will try to reply to your email as quickly as possible, but please allow at least 5 days.